Profile details

Endomysial IgA
Gliadin deamidated lgG
Total IgA*
Tissue Transglutaminase (IgA)
HLA DQ2/DQ8

Sample Reqs

A B

Turnaround

10 days

Special instructions

*To reduce the risk of missing IgA deficient patients, a Total IgA will be run for all low Tissue Transglutaminase IgA results. If IgA deficiency is identified, a reflex deaminated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:

1. Initial TTG IgA samples are received and tested
2. If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
3. If Total IgA is LOW <0.1 g/L then reflex testing for Gliadin IgG test will be undertaken
4. If TTG IgA is HIGH (>/= 10 U/ml then reflex testing for Endomesial IgA will be undertaken as a confirmatory test.

Additional information

• How to order a test
• Guidance on specimen collection
• Specimen transport
• Sample rejection criteria
• Request Forms

Last-updated: 01/08/22

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