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External Quality Assurance


HSL participates in accredited National External Quality Assessment Schemes. These schemes are subscribed to by NHS and private laboratories. Results are subjected to both internal and external quality control.

Details of the laboratories that HSL refers specialist testing to are available from HSL Referrals. These laboratories are UKAS accredited, or of equal accreditation status.

Quality assurance is administered by HSL’s Quality Management Group (QMG).

UKNEQAS ICC & ISH for
Routine IHC & ISH (FFPE) Routine IHC (Cytology) HER2 IHC
ALK IHC
ROS1 IHC
PD-L122C3
PD-L128-8
PD-L1SP142
Mismatch repair (MMR) IHC p16IHC
HER2 FISH + Interpretation ALK FISH + Interpretation ROS1 FISH + Interpretation

UKNEQAS, WEQAS, RIQAS, BIORAD, LABQuality, RCPAQAP for
ACE
ACTH (with PTH) AFP/CEA & HCG
Antibiotics (Gentamicin, Vancomycin and Amikacin)
Anti-HBs Detection Ammonia
Autoimmune (RF and TPO) ASO
B2 Microglobulin
Borrelia IgM/IgG
Cardiac Markers
Clinical Chemistry
CMV IgG/IgM/Avidity CRP & Ultra-Sensitive CRP CSF
Cyclosporin and Tacrolimus DEQAS
Diagnostic Serology Diagnostic Serology Hepatitis Drugs of Abuse
Ethanol
Free Beta HCG and PAPP-A GFR
Glucose/Glucometer Glycated Haemoglobins Guildford Peptides
Haematinics
Healthcontrol Therapeutic Drugs Screen (TDM)
Hepatitis A (with B and C) Hepatitis B Serology Hepatitis C Serology Hepatitis D serology Hepatitis E Serology
HIV Serology
HSV 1 & 2 IgG & typing Homocysteine
HTLV 1 & 2 serology
IGF-1
Immunity Screen
Lipase
Lipid Investigations
Measles and Mumps serology NT-Pro BNP
Paediatric Bilirubins Parasitology
Peptide Hormones
PSA
PTH, ACTH and hCT
Rubella IgG Serology
Salicylate and Paracetamol SARS-CoV-2 (COVID-19) Antibodies Specific Proteins
Steroid Hormones
Syphilis Serology
Thyroglobulin Surveys
Thyroid Hormones
Total IgE
Toxoplasma IgG/M Serology Tumour Markers
Toxoplasma IgM Serology Toxoplasma IgG Serology
Trace Elements
Urine Chemistry
Vitamin D (25 OH)

UKNEQAS for
Automated Differential Leucocyte Count
Blood Film Morphology
Coagulation (Including PoCT Coagulation)
ESR and NRBC (nucleated Rbc) Flow Cytometry
Leukaemia immunophenotyping Myeloperoxidase
Iron stain
Full Blood Count
Haematology
Haematology Analysis
Malaria
Parasite Films
Reticulocyte
Sickle Screening
Thrombophilia Screening Factor assays:
Von Willebrand (vWD) screen Lupus anticoagulant ADAMTS-13 activity and antigen Anti-Xa assay
Plasma viscosities
RCPA
PFA-100 analysis

GENQA, ISFG, EMQN, UKNEQAS, ECAT, LABQUALITY for
Acquired array (CLL/MDS) Acute Leukaemia FISH pilot
Acute Lymphoblastic Leukaemia (ALL) – G banding and FISH
BoBs Rapid Aneuploidy detection
Chlamydia & Gonorrhoea detection by PCR
Constitutional Clinical Cytogenetics (Rounds for Amniocentesis, CVS, Solid Tissue, Blood, Array CGH)
Cystic Fibrosis
Duchenne/Becker Muscular Dystrophy
Hereditary Haemochromotosis (C282Y+H63D) genotyping + reporting
HLA Class I (HLA-A, HLA-B, HLA-C) Tissue Typing (low resolution)
HLA Class II (HLA-DRB1, HLA-DQB1) Tissue Typing (low resolution)
HLA-B27 Genotyping HLA-B57*01 Genotyping
HLA+ Disease Typing Cytochrome P450 2D6/2C19 genotyping
Human Papillomavirus DNA
Mature B & T cell Neoplasms – FISH for CLL and Lymphoma
Mature B & T cell Lymphoma – G-banding
Myeloid (AML/MDS/CML) – G-banding and FISH
Myeloma – sample FISH set up and analysis plus online
NGS AML gene panel
NIPT for aneuploidies
Paternity Testing
Prader-Willi and Angelman Syndromes
QF-PCR Aneuploidy Detection
SARS-CoV-2 (COVID-19) PCR/NAAT
Sexually Transmitted Diseases (CT/NG/MGEN/TV)
Spinal Muscular Atrophy
Thrombophilia (Factor II, V, MTHFR)
Y Microdeletion PCR Assay

QCMD, INSTAND
Atypical Mycobacterium
Adenovirus DNA Viral load
Bacterial 16S
B19 virus DNA Viral load
BK virus DNA Viral load
CMV DBS (dried blood spots)
CMV DNA Plasma Viral load
CMV DNA Whole Blood Viral load
CMV Resistance
EBV DNA Plasma Viral load
EBV DNA Whole Blood Viral load
Enterovirus RNA
Gastroenteritis Virus Panel
Hepatitis B Genotyping
Hepatitis B Drug Resistance Typing
Hepatitis B Viral Load
Hepatitis C genotyping
Hepatitis C Resistance genome detection (NS5a & b)
Hepatitis C Resistance Typing (NS3 & NS5a)
Hepatitis C Viral Load
Hepatitis D Virus Viral load and Qualitative PCR
Hepatitis E Virus Viral load and Qualitative PCR
HIV-1 Drug Resistance (Pol)
HIV-1 Drug Resistance (Integrase)
HIV-1 RNA Viral load
HIV-1 RNA Qualitative PCR
HIV-1 Tropism Genome Detection
HIV-2 Viral load and Qualitative PCR
HSV 1&2 DNA
HSV Drug Resistance
Human Herpes virus 6 DNA
Human Herpes virus 8 DNA
Influenza Haemagglutinin typing
JC virus DNA
Measles and Mumps PCR
MERS Coronavirus
Parechovirus RNA
Respiratory panel I
Respiratory panel II
SARS-CoV-2 (COVID-19) PCR/NAAT
Syphilis PCR
Transplantation Virus Panel
VZV DNA

UKNEQAS, QCMD for
AAFB for Microscopy + Mycobacterium Culture
Antifungal Panel
Antifungal Susceptibility
Antimicrobial Susceptibility
Clostridium Difficile + MRSA Screening
Cryptococcal Antigen Detection (Pilot Scheme)
Faecal Parasitology
Faecal Haemoglobin EQA scheme
Faecal Markers for Inflammation (Calprotectin)
Fungal Biomarkers (Pilot Scheme) General Bacteriology
Genital Pathogens
Molecular detection of Mycobacteria Mycology
Urinary Antigen: Legionella
Urinary Antigens (Legionella and Pneumococcal antigen)
WEQAS Urinanalysis scheme

UKNEQAS – Immunology, Immunochemistry and Allergy for
ELISA
ANA/DNA
Autoimmune Serology ANCA/GBM Antibodies
Allergen Component Testing Bullous Dermatosis Antibodies C1IN & Functional Complement Coeliac Disease Antibodies Diabetic markers
General Autoimmune serology
Interferon Gamma Release Assay (IGRA)
Myositis Antibodies Cardiolipin IgG & IgM Screen Specific Microbial Antibodies

UKNEQAS – Microbiology for
HIV Serology
Syphilis Serology
HepB surface Ag
HepC Serology
Lyme (Borelia) Serology HepE Serology

Labquality EQAS for
Anti Streptolysin O
CMV IgG avidity
HSV 1 and 2 (IgG)
Helicobacter pylori IgG Serology

RCPAQAP (The Royal College of Pathologists of Australasia Quality Assurance Programs) for
Scleroderma Autoantibodies Brucella Serology Legionella Serology Chlamydia Serology
Striated Muscle

INSTAND e.V. for
Adrenal Antibodies
Hep E IgG & IgM Serology

CSCQ for
Lyme (Borelia) serology
IFQ – Lubeck for
Liver Autoantibodies

UKNEQAS for Microbiology for
Molecular Detection of HPV

NHSCSP EQA scheme for
Gynaecological Pathology
The preparation and staining of cervical liquid based cytology samples

Hologic EQA Scheme for
ThinPrep Stain

UKNEQAS for
Semen Analysis Scheme

Accredited by British Standards Institute
ISO/IEC 27001:2013